By Frederick Kavanagh
Analytical Microbiology, quantity II is a six-chapter paintings that covers the numerous adjustments and enhancements made within the thought and perform of analytical microbiology.
The first bankruptcy is dedicated to the theoretical features of assaying of particular compounds. those issues are by means of discussions of the theoretical and functional elements of diffusions assays, in addition to the theoretical advancements of photometric equipment of assay, together with their development due to automation. A bankruptcy explores the assay equipment for numerous antibiotic teams. one other bankruptcy discusses the advances in assay expertise and analytically vital interrelations one of the folic acid complicated. The final bankruptcy describes an easy diffusion procedure designed for the assay of yes amino acids in a large choice of samples.
This ebook will end up precious to analytical microbiologists.
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Additional info for Analytical Microbiology. Volume II
In " B i o c h e m i s t r y of B a c t e r i a l G r o w t h , " p p . 136 a n d 148. Blackwell, O x f o r d . M a y r - H a r t i n g , A . (1964). / . Pathol. Bacteriol. 87, 2 5 5 . M a y r - H a r t i n g , Α . , a n d S h i m e l d , C . (1965). Zentralbl. Bakteriol. Parasitenk. , Abt. 1: Orig. 196, 2 6 3 . M e d o w , P . , a n d Pirt, S. J. (1969). " M i c r o b i a l G r o w t h — S y m p o s i u m . " C a m b r i d g e U n i v . Press, L o n d o n a n d N e w Y o r k . M e y n e l l , G .
Pharm. Sei. 57, 8 7 1 . A s h e s h o v , I. N . , a n d Strelitz, F . (1945). Science 101, 6 2 1 . Coffey, H . F . , a n d K u z e l , N . R . (1967). U . S . P a t . 3,316,854. K a v a n a g h , F . (1960). Advan. Appl. Microbiol. 2 , 7 1 . K n u d s e n , L. F . , a n d R a n d a l l , W . A . (1945). / . Bact. 50, 187. K u z e l , N . R . , a n d Coffey, H . F . (1966). Amer. Soc. Microbiol. , 1966 p . 0 0 0 L e v i n , J. D . (1968). Ann. Ν. Y. Acad. Sei. 153, 595. R a n d a l l , W . Α .
In the general case, the square of the diameter of the zone of inhibition is proportional to the logarithm of the concentration of the substances causing the response. The linear (X vs. log C) dose-response line is an accurate representation of a short range of concentrations. Often the straight line may be used if the largest concentration of the active substance is only four times the smallest concentration. If the range is more than fourfold, very careful and extensive work may be required to demonstrate that the line is truly straight.